Login to PubMed and first run your search.
Once you are satisfied that your search is retrieving the kind of information which you need, click on the save search link in blue which appears below the search box.
Sign in to My NCBI
Give your search a name which clearly indicates the subject, and click save.
Decide whetther or not you would like to receive email updates on the subject and specify how often the search should be re-run, the format in which you wish to receive the results, and limit the number of references sent.
Remember that you can later change all of the settings, or cancel the search.
Even if you have not arranged to have updates emailed to yourself, you can repeat one of your saved searches at any time.
Login to PubMed and sign in to My NCBI
Open My Saved Data